Dr. Aaron Smargon
Postdoctoral Scholar, University of California, San Diego, School of Medicine, Department of Cellular and Molecular Medicine
Research Profile
RNA-targeting CRISPR systems: from metagenomic discovery to transcriptomic engineering
Thursday, September 26
2 PM
RRI 101
Abstract: The deployment of RNA-guided DNA endonuclease CRISPR-Cas technology has led to radical advances in biology. As the functional diversity of CRISPR-Cas and other prokaryotic defense systems is further explored, RNA manipulation has emerged as a powerful new mode of CRISPR-based engineering. In this seminar I chart the most recent progress in the RNA-targeting CRISPR-Cas (RCas) field and illustrate how a continuing evolution in scientific discovery translates into applications for RNA biology and insights into the mysteries, obstacles, and alternative technologies that lie ahead.
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