Sunday, March 26, 2017

Why Don't They Understand Me? Pronunciation in a U.S. Business Setting

Why Don't they Understand Me? Pronunciation in a U.S. Business Setting
Thursday, March 30, 2017, 3:30 PM to 5:00 PM
Taper Hall (THH) 201 

While English is the lingua-franca in U.S. business settings, the variety of English accents can cause communication breakdowns. This workshop, presented by American Language Institute Master Lecturer Barry Griner, focuses on areas of pronunciation that you can adjust so that your accent is more easily understood by future colleagues and employers.

Small Molecule-induced Cell Fate Reprogramming

From gene list to biology part I: pathways and diseases

Norris Medical Library Bioinformatics Service is pleased to present “From gene list to biology part I: pathways and diseases”.  This workshop will explain the basics of functional enrichment analysis and showcase how to explore the biological impact of your differentially expressed genes.

·         What is functional enrichment analysis
·         Gene Ontology and biological pathways
·         Perform and interpret Core Analysis in Ingenuity Pathway Analysis (IPA)

Time: Noon - 1pm, Wednesday, March 29th
Location: Norris Medical Library, West Conference Room (basement level in the library)
Lunch will be provided
Registration is mandatory.  Seating is limited to 45 attendees.

Integrated Large-Scale Heterogeneous Measurements in Single Cells

David Van Valen, M.D. Ph.D.
Postdoctoral Fellow, Department of Bioengineering 
Stanford University

"Integrated Large-Scale Heterogeneous Measurements in Single Cells"

Wednesday, March 29, 2017
11:00 a.m. - 12:00 p.m.
Q & A to follow

Harkness Auditorium
HSC - Clinical Sciences Building, 2nd Floor
2250 Alcazar Street, CSC 250, Los Angeles, CA

Individual cells differ markedly in their behavior, and these differences often confound attempts to determine biological mechanism using bulk methods. In this talk, we present work connecting recent advances in imaging, genomics, and machine learning to meet this challenge. We demonstrate how deep learning can be used to identify single cells in microscope images, paving the way for fully automated analysis workflows. We also present a new method that connects live-cell imaging with single-cell genomics to measure signaling dynamics and a genome wide gene expression profile in the same individual cell. We use this new approach to discover how heterogeneous NF-κB dynamics are decoded by the genome.

Emerging Trends in Heart Valve Engineering and Translation to Clinical Medicine

Emerging Trends in Heart Valve Engineering and Translation to Clinical Medicine

Wednesday, March 29th, 2017
1pm RRI Conference Room 101

Valvular heart disease is an increasingly common cause of cardiovascular disease in the United States and is equally impactful around the globe. This burden of disease leads to over 300,000 heart valve replacement surgeries each year worldwide. It is anticipated that the number of patients requiring valve replacement worldwide will triple by 2050, leading some to describe heart valve disease as “the next cardiac epidemic”.
Heart valves cannot naturally regenerate or heal. The current approaches to heart valve disease is either to repair or replace a native heart valve. Heart valve engineering is a branch of biomedical engineering focused on the research and development of devices to replace or repair a diseased heart valve. At my lab, we have four different heart valve research pipelines, including a transcatheter aortic valve (FoldaValve), a transcatheter system for atrioventricular valves, a bi-leaflet mitral valve and a hybrid tissue-engineered valve. In this presentation, I will go over different aspects of the heart valve engineering, clinical unmet needs and discuss the research and development related to the heart valves currently being developed and studied at my laboratory.

Arash Kheradvar, M.D., Ph.D., FAHA is an Associate Professor of Biomedical Engineering and Medicine at the University of California, Irvine. His research interests are focused on developing novel heart valves, cardiac fluid dynamics, and new cardiac imaging technologies. He is the author of more than 45 journal articles and the lead inventor of 45 issued and pending patents in cardiovascular area, mainly on heart valve technologies and imaging modalities. Dr. Kheradvar received M.D. from Tehran University of Medical Sciences in 2000 and a Bioengineering Ph.D. from Caltech in 2006. He is an elected Fellow to the American Heart Association by two councils of Cardiovascular Radiology and Intervention, and Cardiovascular Surgery and Anesthesia. For more information see

Science in a Regulatory Agency Event

Science in a Regulatory Agency
Thursday, April 6th, 2017
ZHS 200, 1pm (lunch is included)

Being a scientist in a regulatory agency holds challenges unique in the scientific community. Such a position requires a clear understanding of the differences between science and policy, and requires that a scientist is continually aware of the need to protect and maintain her independence and objectivity. While scientists in the academic community have the freedom to make policy recommendations, researchers in a regulatory agency must stop short of advocating for particular policy choices, while at the same time conducting science that informs those policy choices. The line between informing and advocating is not always clear, especially as science becomes increasingly politicized. We will discuss some of the sensitivities, challenges, and opportunities that come with doing science in a regulatory setting.

Dr. C.A. (Andy) Miller is the Associate Director for Climate with EPA’s Office of Research and Development (ORD) and represents EPA at the US Global Change Research Program. Most of his 26 years have been with ORD, where he conducted research on characterization and control of combustion-generated air pollution and on climate change impacts, adaptation, and mitigation. He also spent several months working for the Office of Air and Radiation on a regulation to control oxides of nitrogen from power plants. Andy has served as a team lead for PM research, and was Acting National Program Director for ORD’s PM research program. He received a B.S. and M.S. in mechanical engineering from the University of Arizona, and a Ph.D. in mechanical engineering from North Carolina State University. He is currently located in the Southern California Field Office, part of EPA’s Region 9, but continues to work for ORD from Los Angeles.

Wednesday, March 22, 2017

AIM For Mental Health

USC is hosting a Mental Health Awareness event, called AIM, on Thursday, March 30, from 5-7 PM.  There will be food, resources, speakers, live music, info tables, and freebies for students.