Salk Institute for Biological Studies
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A new model for telomerase: replication fork collapse drives telomere length homeostasis
Friday, April 6
12:00 PM
RRI 101
Abstract: Telomeres, the natural ends of linear chromosomes, must be replenished by the enzyme telomerase to ensure continuous proliferation of cells. The prevailing model in the field assumes that telomerase elongates chromosome termini only after DNA replication is complete. Dr. Lundblad will propose that the major substrate for telomerase is instead generated by errors that occur during replication of duplex telomeric DNA..
Host: Oscar Aparicio
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