Tuesday, April 19, 2016

MB Seminar Series | "DNA Repair and Precision Medicine.”

Richard Pomerantz
Temple University
Lewis Katz School of Medicine
Fels Institute for Cancer Research

Friday, April 22, 2016
12:00 PM
RRI 101
Host: Xiaojiang Chen

Monday, April 11, 2016

3rd Annual Zilkha Symposium on Alzheimer Disease and Related Disorders


Microorganisms battle it out within algal blooms

Jed Fuhrman and David Needham of biological sciences discover that algal blooms in the ocean encompass microscopic skirmishes, with the front lines shifting on a daily basis.

By Robert Perkins - March 8, 2016

















A microscopic image shows the type of phytoplankton and bacteria observed by USC researchers during a study of algal blooms. Photo courtesy of David Needham and Jed Fuhrman.

An unseen war raging among the ocean’s tiniest organisms has significant implications for understanding the ocean’s role in climate change, according to a new study...

For the full story, click here.

Summer Fellowship Boot Camp

Dear colleagues, we are delighted to let you know that as part of our DIA initiative, the Graduate School will host an expanded Summer Fellowship Boot Camp for incoming and rising second year PhD students. If appropriate, please share the information below with eligible candidates.

The boot camp is a 10-day intensive writing workshop in which participants will complete an application for one of the following opportunities:
•         National Science Foundation, Graduate Research Fellowship Program
•         Ford Foundation Pre-Doctoral Fellowship
•         Paul and Daisy Soros Fellowship for New Americans

Participants will receive a $1,000 stipend for housing and other expenses while attending the boot camp. In addition, participants who submit a complete application to one of the identified fellowships in fall 2016 may be eligible for a travel or research award of up to $1,000.

Participants are expected to attend all of the scheduled activities and to work on drafts of their proposals while not in sessions. Participants will meet as a large group on Wednesday August 3 for a full day of activities. Subsequent sessions will be organized around specific fellowship applications. Students from STEM fields interested in applying for the NSF GRFP will meet in the mornings. Students interested in the Ford, Soros or NSF GRFP in social science fields will meet in the afternoons. On most session days, there will be an optional lunch for all students from 12:00 - 1:00 pm.

Eligibility: Boot camp applicants must meet the requirements of the identified fellowships. Applicants must be a US citizen, US national, or permanent resident and either a newly admitted PhD student or a rising second year PhD student in fall 2016.

Information about specific eligibility requirements for the various fellowships is available on these websites:
NSF GRFP: https://www.nsfgrfp.org/
Ford Pre-Doctoral: http://sites.nationalacademies.org/PGA/FordFellowships/index.htm
Soros: http://www.pdsoros.org/competition/

To apply, please complete the form located here: https://goo.gl/3mTsfA. More information is available from the USC Graduate School at gradfllw@usc.edu. Applications are due on June 3, 2016. Applications will be reviewed by an interdisciplinary faculty committee and acceptance decisions will be sent out before the end of the month.

All the best, Meredith


Meredith Drake Reitan, MPL, PhD
Associate Dean for Graduate Fellowships
Graduate School
Office of the Provost
Adjunct Associate Professor
Sol Price School of Public Policy
University of Southern California
mereditd@usc.edu


2016 Mentoring Award Recipient | Dr. Remo Rohs

Each year the University of Southern California recognizes faculty members across the university who have demonstrated a commitment to mentoring. This year over 150 deserving faculty were nominated and 21 were selected.

Recipient List

ChemBio Seminar Series | "High Resolution CryoEM Structural Analysis of Heterogeneous Macromolecular Machines"

Thursday, April 14, 2016, 12:30pm in the Seaver Science Auditorium
SSL next to the library

Dr. Dmitry Lyumkis
Salk Helmsley Fellow, Laboratory of Genetics
The Salk Institute for Biological Studies

Abstract:
Single particle cryo-electron microscopy (cryoEM) is becoming a fundamental component of a
structural biologist’s toolkit, as improvements in instrumentation, software, automation, and
specimen preparation are making this technique increasingly powerful for the analysis of
macromolecules and macromolecular complexes. One of the primary advantages of the
methodology is the ability to analyze heterogeneous macromolecular assemblies, i.e. those that
exhibit either conformational mobility within distinct regions or compositional heterogeneity
exhibited by loosely and sub-stoichiometrically associated components. By employing
classification techniques, it is possible to place each individual particle image into one of several,
potentially many, groups, according to homogeneity. I will present three biological stories, which
center around and build upon the principles of high resolution cryoEM imaging and heterogeneity
analysis, each differing in the level of structural complexity. First, I will describe our structural
insights into a novel architecture of a retroviral integration complex called an intasome. I will then
describe how we used cryoEM to solve the structure of a very small protein complex by cryoEM
standards (150 kDa) to near-atomic resolution, wherein, crucially, we teased out the functionally
relevant enzymatic form using just 2% of the data. Finally, I will describe our current efforts
toward understanding the structural complexity and dynamic assembly underlying ribosome
biogenesis.

The scientific community is invited to attend.

NSF CAREER Award Educational Outreach Workshop

Tuesday, May 17, Noon - 1:30pm
Loker Hydrocarbon Institute (LHI) 307, Olah Library
Co-Sponsored by the Loker Hydrocarbon Research Institute

Most NSF funding programs prioritize an integrated educational/outreach program as part of the proposed project. This is particularly critical for CAREER projects. Because many NSF applicants find it challenging to identify strong educational/outreach plans for NSF awards, the CET is reprising its popular workshop in which recent NSF grantees and panelists will provide feedback on proposals in development and discuss how they might review or what changes could optimize their probability of funding.

Participants are encouraged to submit a pre-copy or summary of their educational/outreach plan to the host to ensure that appropriate reviewers are in attendance.

All NSF applicants and prospective applicants are welcomed.

Presented by: Travis Williams, CET Faculty Fellow and Associate Professor of Chemistry and recent CAREER Recipient, Philip Taylor, USC Dornsife Executive Director of Research Advancement; and a panel of recent NSF grantees and reviewers.
RSVP to travisw@usc.edu