Thursday, May 19, 2016
Wednesday, May 18, 2016
Post Doc Position Available
Please be advised that applications for the inaugural D.W. Hearst, Jr. Foundation Post-doctoral Scholar position will be accepted until July. Here is the description of the position:
David Whitmire Hearst, Jr. Foundation Post-doctoral Scholar
A post-doctoral fellow is sought to represent the David Whitmire Hearst Jr. Foundation as its inaugural scholar. The post-doctoral scholar will study in the laboratory of principle investigator Charles Spruck, Ph.D., at the Sanford|Burnham|Prebys Medical Discovery Institute in La Jolla, CA. The host laboratory's research interests include regulation of cell division control, metastasis progression in breast and other cancers, and developing novel cancer therapeutics.
Candidates should have strong background in molecular biology techniques and completed less than 2 years of post-doctoral studies. Interested candidates should send their CV/Biosketch, including a list of three references, to cspruck@SBPdiscovery.org. The best candidates would likely be current graduate students or early-stage post-docs at either the Norris Cancer Center on the medical campus (where Dr. Spruck completed his PhD studies) or the department of Molecular Biology on the main campus.
Charles Spruck, Ph.D.
Tumor Initiation and Maintenance Program
NCI-designated Cancer Center
Sanford|Burnham|Prebys Medical Discovery Institute
10901 N. Torrey Pines Rd.
La Jolla, CA 92037
(858)-646-3100, x5128
cspruck@SBPdiscovery.org
David Whitmire Hearst, Jr. Foundation Post-doctoral Scholar
A post-doctoral fellow is sought to represent the David Whitmire Hearst Jr. Foundation as its inaugural scholar. The post-doctoral scholar will study in the laboratory of principle investigator Charles Spruck, Ph.D., at the Sanford|Burnham|Prebys Medical Discovery Institute in La Jolla, CA. The host laboratory's research interests include regulation of cell division control, metastasis progression in breast and other cancers, and developing novel cancer therapeutics.
Candidates should have strong background in molecular biology techniques and completed less than 2 years of post-doctoral studies. Interested candidates should send their CV/Biosketch, including a list of three references, to cspruck@SBPdiscovery.org. The best candidates would likely be current graduate students or early-stage post-docs at either the Norris Cancer Center on the medical campus (where Dr. Spruck completed his PhD studies) or the department of Molecular Biology on the main campus.
Charles Spruck, Ph.D.
Tumor Initiation and Maintenance Program
NCI-designated Cancer Center
Sanford|Burnham|Prebys Medical Discovery Institute
10901 N. Torrey Pines Rd.
La Jolla, CA 92037
(858)-646-3100, x5128
cspruck@SBPdiscovery.org
Monday, May 9, 2016
New complimentary webinar from Science
CRISPR/Cas9 in drug discovery: Applications in target discovery, validation, and hit screening
You are invited to hear our panel of experts on May 11, 2016, in this live, online educational seminar. For more information and complimentary registration visit: webinar.sciencemag.org
Date: Wednesday, May 11, 2016
Time: 12 noon Eastern, 9 a.m. Pacific, 5 p.m. UK, 6 p.m. Central Europe
Duration: 1 hour
Register Now
About This Webinar
The CRISPR/Cas9 system allows for unprecedented ease and control when editing the genome. Its potential impact on drug discovery is vast, including enabling gene and cell replacement therapies, identifying novel drug targets through functional genomic screens, and simplifying the production of disease models using permanent knockouts for validating therapy targets and testing drug efficacy. But in practical terms, how is CRISPR/Cas9 currently being applied, and where might the future challenges and pitfalls be? Furthermore, how do assays based on the new CRISPR/Cas9 technology compare with current screening methodologies, particularly those using small interfering RNA (siRNA)?
During the webinar, our expert panel will address:
• Areas of the drug discovery process where gene editing will have the most immediate and long term impact
• The current and future role of CRISPR/Cas9 in target discovery, hit identification, and lead optimization (compared with siRNA screening)
• The challenges that CRISPR/Cas9 brings to screening and assay development, particularly with respect to cell analysis
• The importance of carrying out binding studies following gene editing.
The presentations will be followed by a live Q&A session with the online audience.
Participants:
Lorenz Mayr, Ph.D.
AstraZeneca
Cambridge, U.K.
Ralph Garippa, Ph.D.
Memorial Sloan Kettering Cancer Center
New York, NY
Register at:
webinar.sciencemag.org
Questions? E-mail: webinar@aaas.org.
Produced by the Science/AAAS Custom Publishing Office and sponsored by: General Electric
You are invited to hear our panel of experts on May 11, 2016, in this live, online educational seminar. For more information and complimentary registration visit: webinar.sciencemag.org
Date: Wednesday, May 11, 2016
Time: 12 noon Eastern, 9 a.m. Pacific, 5 p.m. UK, 6 p.m. Central Europe
Duration: 1 hour
Register Now
About This Webinar
The CRISPR/Cas9 system allows for unprecedented ease and control when editing the genome. Its potential impact on drug discovery is vast, including enabling gene and cell replacement therapies, identifying novel drug targets through functional genomic screens, and simplifying the production of disease models using permanent knockouts for validating therapy targets and testing drug efficacy. But in practical terms, how is CRISPR/Cas9 currently being applied, and where might the future challenges and pitfalls be? Furthermore, how do assays based on the new CRISPR/Cas9 technology compare with current screening methodologies, particularly those using small interfering RNA (siRNA)?
During the webinar, our expert panel will address:
• Areas of the drug discovery process where gene editing will have the most immediate and long term impact
• The current and future role of CRISPR/Cas9 in target discovery, hit identification, and lead optimization (compared with siRNA screening)
• The challenges that CRISPR/Cas9 brings to screening and assay development, particularly with respect to cell analysis
• The importance of carrying out binding studies following gene editing.
The presentations will be followed by a live Q&A session with the online audience.
Participants:
Lorenz Mayr, Ph.D.
AstraZeneca
Cambridge, U.K.
Ralph Garippa, Ph.D.
Memorial Sloan Kettering Cancer Center
New York, NY
Register at:
webinar.sciencemag.org
Questions? E-mail: webinar@aaas.org.
Produced by the Science/AAAS Custom Publishing Office and sponsored by: General Electric
Thursday, May 5, 2016
Post Doctoral Position Available at USC
USC Prof., Kelvin J. A. Davies, is looking for a motivated post-doctoral fellow to join his lab at the University of Southern California to study stress adaptation, protein oxidation & protein degradation
focusing on signal transduction pathways for regulation of the Proteasome and the mitochondrial Lon protease in oxidative stress.
Protease subunits and regulators are differentially expressed and exhibit differential binding/activities during stress. The Davies lab. is studying the mechanisms by which protein turnover and stress resistance are regulated during reversible adaptation.
Graduating Ph.D. students or recent Ph.D.’s with skills in biochemical methods and molecular biology techniques are encouraged to apply. Interested candidates should contact Kelvin Davies directly by e-mail at kelvin@usc.edu.
focusing on signal transduction pathways for regulation of the Proteasome and the mitochondrial Lon protease in oxidative stress.
Protease subunits and regulators are differentially expressed and exhibit differential binding/activities during stress. The Davies lab. is studying the mechanisms by which protein turnover and stress resistance are regulated during reversible adaptation.
Graduating Ph.D. students or recent Ph.D.’s with skills in biochemical methods and molecular biology techniques are encouraged to apply. Interested candidates should contact Kelvin Davies directly by e-mail at kelvin@usc.edu.
Tuesday, May 3, 2016
Army Research Laboratory (ARL) - Distinguished Postdoctoral Fellowships
I ask your assistance in forwarding this message to graduate students in your department informing them of an outstanding fellowship opportunity with the Army Research Laboratory (ARL). The ARL Distinguished Postdoctoral Fellowship provides recipients the opportunity to pursue independent research while working alongside some of the nation's best scientists and engineers.
The Army Research Laboratory invites exceptional young researchers to apply for the ARL Distinguished Postdoctoral Fellowship. Applicants must display extraordinary ability in scientific research and show clear promise of becoming outstanding leaders. Successful candidates will have tackled a major scientific or engineering problem during their thesis work or will have provided a new approach or insight, as evidenced by a recognized impact in their field.
Eligibility criteria
• Applicants must have completed all the requirements for a Ph.D. or Sc.D. degree in the physical sciences, life sciences, computational sciences, behavioral sciences, or engineering and must be within three years from the date of their degree at the time of application.
• Selected fellows must pass a Department of Defense clearance process, requiring a background security investigation.
• Applicants must demonstrate exceptional qualifications with respect to academic and scholarly achievement, as evidenced by research and publication.
Fellowship terms and benefits
• Stipend - $100,000 annually
• Health insurance (including dental and vision)
• Paid relocation and a professional travel allowance
• Appointments are for one year renewable for up to three years based on performance.
Fellowship appointments require a full-time commitment to the research program at ARL, and Fellows must be in residence at ARL during the entire period of the appointment.
More detailed information and an online application can be found at http://sites.nationalacademies.org/PGA/Fellowships/ARL.
Questions should be directed to the NRC at 202-334-3560 (phone) or ARLDPF@nas.edu.
Thank you for your assistance.
Sincerely yours,
H. Ray Gamble
Director, Fellowship Programs Office
National Academies of Sciences, Engineering, and Medicine
500 Fifth Street NW
Washington, DC 20001
The Army Research Laboratory invites exceptional young researchers to apply for the ARL Distinguished Postdoctoral Fellowship. Applicants must display extraordinary ability in scientific research and show clear promise of becoming outstanding leaders. Successful candidates will have tackled a major scientific or engineering problem during their thesis work or will have provided a new approach or insight, as evidenced by a recognized impact in their field.
Eligibility criteria
• Applicants must have completed all the requirements for a Ph.D. or Sc.D. degree in the physical sciences, life sciences, computational sciences, behavioral sciences, or engineering and must be within three years from the date of their degree at the time of application.
• Selected fellows must pass a Department of Defense clearance process, requiring a background security investigation.
• Applicants must demonstrate exceptional qualifications with respect to academic and scholarly achievement, as evidenced by research and publication.
Fellowship terms and benefits
• Stipend - $100,000 annually
• Health insurance (including dental and vision)
• Paid relocation and a professional travel allowance
• Appointments are for one year renewable for up to three years based on performance.
Fellowship appointments require a full-time commitment to the research program at ARL, and Fellows must be in residence at ARL during the entire period of the appointment.
More detailed information and an online application can be found at http://sites.nationalacademies.org/PGA/Fellowships/ARL.
Questions should be directed to the NRC at 202-334-3560 (phone) or ARLDPF@nas.edu.
Thank you for your assistance.
Sincerely yours,
H. Ray Gamble
Director, Fellowship Programs Office
National Academies of Sciences, Engineering, and Medicine
500 Fifth Street NW
Washington, DC 20001
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